Peter Cistulli

Oral appliance therapy for obstructive sleep apnea: Ready for prime time (a state of the art review of the field)

Peter Cistulli MD, PhD, MBA

Keynote Summary: Oral appliances (OA) have emerged as the leading alternative to positive airway pressure (PAP) for Obstructive Sleep Apnoea (OSA) treatment. There is a strong evidence base demonstrating OA therapy improves OSA in the majority of patients, including some with more severe disease. They are generally well tolerated, and patients often prefer OA over PAP treatment. Despite the superior efficacy of PAP over OA, randomized controlled trials comparing the two indicate similar improvement in health outcomes such, as sleepiness, quality of life, driving performance, blood pressure, and other cardiovascular measures. The evidence base strongly supports the use of OA therapy in the management of OSA.

Biosketch: Peter Cistulli holds the ResMed Chair in Sleep Medicine at the University of Sydney, where he leads the Sleep Research Theme within the multidisciplinary Charles Perkins Centre, and also Heads the Discipline of Sleep Medicine in the Faculty of Medicine and Health. He is also Director of the Sleep Medicine Program in the Department of Respiratory and Sleep Medicine at Royal North Shore Hospital, Sydney. He is an active clinician researcher with 28 years experience in the fields of respiratory and sleep medicine. His thematic research has focused on the pathophysiology of Sleep-disordered Breathing, and novel approaches to therapy, particularly with oral appliances. This work has been predominantly funded by the NHMRC of Australia, and he has achieved in excess of $14M in competitive funding. He has an extensive publication record, and has received international awards for his academic contributions to the sleep field. His interdisciplinary research program involves numerous national and international collaborations. He is a former President of the Australasian Sleep Association and a former board member of the Sleep Health Foundation.